Peppermint
Overview
Peppermint is a plant in the mint family. The leaf and oil are used as medicine.
Peppermint oil is used for a long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS). It is also used for indigestion (dyspepsia), spasms in the bowel, hard, painful breasts in breast-feeding women, bed sores (pressure ulcers), and tension headache. It is also used for many other conditions, but there is no good scientific evidence to support many of these uses.
In foods and beverages, peppermint is a common flavoring agent.
In manufacturing, peppermint oil is used as a fragrance in soaps and cosmetics, and as a flavoring agent in pharmaceuticals.
Classification
Is a Form of:
Plant
Primary Functions:
Stomach pain
Also Known As:
Black Peppermint, Brandy Mint, Extract of Mentha Piperita
How Does It Work?
Peppermint oil seems to reduce spasms in the digestive tract. When applied to the skin, it can cause surface warmth, which relieves pain beneath the skin. It may also help to "cool" the skin and relieve itching.
Uses
- A long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS).Most research shows that taking peppermint oil by mouth reduces stomach pain, bloating, gas, and bowel movements in people with IBS. Most trials have used specific peppermint oil products (Colpermin by Tillotts Pharma; Mintoil by Cadigroup; IBgard by IM HealthScience, Tempocol).
- Relaxing the colon during a barium enema examination. Using peppermint oil as an ingredient in enemas seems to relax the colon during barium enema examinations. Also, taking peppermint oil by mouth before the start of a barium enema seems to decrease spasms.
- Hard, painful breasts in breast-feeding women. Research shows that breastfeeding women who apply peppermint oil in gel, cream, or water to their skin have less cracked skin and pain in the nipple area.
- Indigestion (dyspepsia). Taking a specific product containing peppermint oil and caraway oil (Enteroplant or Menthacarin by Dr Willmar Schwabe Pharmaceuticals) by mouth seems to reduce feelings of fullness, discomfort, pain, and stomach spasms. It also appears to improve quality of life. Another specific combination product containing peppermint (Iberogast by Steigerwald Arzneimittelwerk GmbH) also seems to improve symptoms of heartburn, including severity of acid reflux, stomach pain, cramping, nausea, and vomiting. The combination includes peppermint leaf plus clown's mustard plant, German chamomile, caraway, licorice, milk thistle, angelica, celandine, and lemon balm. Another similar combination product containing peppermint leaf, clown's mustard, German chamomile, caraway, licorice, and lemon balm (STW 5-II by Steigerwald Arzneimittelwerk GmbH) also seems to help. However, peppermint oil does not seem to help indigestion when taken as a single ingredient after surgery.
- Spasms caused by a certain procedure (endoscopy) used to view the inside of the body. Research shows that peppermint oil can reduce spasms in people having an endoscopy. Some research also shows that peppermint oil can reduce pain during this procedure.
- Bed sores (pressure ulcers). Research shows that applying a gel containing peppermint oil can prevent bed sores in people who must stay in bed for at least 2 weeks due to head trauma.
- Tension headache. Applying peppermint oil to the skin seems to help relieve tension headaches.
Recommended Dosing
The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- For a long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS): One to two enteric-coated capsules each providing 0.2 mL or 180-225 mg of peppermint oil three times daily has been used. Most trials have used specific peppermint oil products (Colpermin by Tillotts Pharma; Mintoil by Cadigroup; IBgard by IM HealthScience).
- For indigestion (dyspepsia): A specific product containing 90 mg of peppermint oil and 50 mg of caraway oil (Enteroplant or Menthacarin by Dr Willmar Schwabe Pharmaceuticals), taken two or three times daily for up to 4 weeks has been used. A specific combination product containing peppermint leaf and several other herbs (Iberogast by Steigerwald Arzneimittelwerk GmbH) has been used in a dose of 1 mL three times daily. A similar herbal preparation containing extracts from clown's mustard, German chamomile flower, peppermint leaves, caraway, licorice root, and lemon balm (STW 5-II by Steigerwald Arzneimittelwerk GmbH), 1 mL taken three times daily for up to 8 weeks, has been used.
- For spasms caused by a certain procedure (endoscopy) used to view the inside of the body: Enteric-coated capsules containing 187 mg of 0.2 mL of peppermint oil have been taken 4 hours before a colonoscopy.
APPLIED TO THE SKIN:
- For hard, painful breasts in breast-feeding women: Peppermint oil cream or gel 0.2% has been applied 1-3 times every day for 2 weeks. Also, a solution containing peppermint oil has been applied after every breastfeeding for 2 weeks.
- For spasms caused by a certain procedure (endoscopy) used to view the inside of the body: 20 mL of spray containing 0.4-1.6% peppermint oil applied to the antrum during endoscopy has been used. Also 16-40 mL of solution containing peppermint oil has been applied into the lumen during endoscopy.
- For bed sores (pressure ulcers): A gel containing peppermint oil 0.2% applied three times daily for up to 14 days has been used.
- For tension headaches: 10% peppermint oil in ethanol solution applied across the forehead and temples, repeated after 15 and 30 minutes, has been used.
BY ENEMA:
- For relaxing the colon during a barium enema examination: 8 mL of peppermint oil was added to 100 mL water along with a surface active agent, Tween 80. The insoluble fraction was removed, then 30 mL of the remaining peppermint solution was added to 300 mL of the barium solution. Also, 16 mL of peppermint oil and 0.4 mL of polysorbate was diluted in 2 liters of purified water, then 30 mL of the peppermint solution was added to barium paste suspended in 370 mL of water in an enema bag, and 10 mL of the peppermint solution was added to the enema tubing.
CHILDREN
BY MOUTH:
- For a long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS): One or two enteric-coated capsules containing 0.2 mL of peppermint oil per capsule (Colpermin by Tillotts Pharma) has been taken three times daily for 2 weeks by children aged 8 years and older.
Peppermint Supplements Frequently Asked Questions
What is peppermint oil capsules good for?
Benefits of Peppermint Oil
Several studies suggest that enteric-coated peppermint oil capsules -- which allow the oil to pass through the stomach so it can dissolve in the intestines -- may help relieve common symptoms of irritable bowel syndrome such as abdominal pain, bloating, and gas.
Is it safe to take peppermint capsules everyday?
Peppermint oil capsules help to relieve tummy (abdominal) pain and bloating associated with conditions like irritable bowel syndrome. Take one or two capsules three times a day, preferably about an hour before meals.
Is Peppermint tablets good for bloating?
She added: “It also has a relaxing effect on the intestinal tract to relieve spasm. Peppermint is therefore taken to relieve bloating, indigestion, colic, intestinal cramps, flatulence, diverticulitis and irritable bowel syndrome. You can drink peppermint tea as required, or take a peppermint capsule (100mg) per day.
What medications does peppermint interfere with?
What other drugs will affect peppermint?
- iron supplements;
- cyclosporine (neoral, Sandimmune);
- any antibiotic or antifungal medicine;
- medicinefor seizures;
- medicinesfor heart conditions or high blood pressure; or.
- medicinesto decrease stomach acid.
What are the side effects of peppermint oil capsules?
- allergic reactions.
- burning mouth syndrome.
- diarrhea with anal burning.
- mouth ulcers.
What are the side effects of peppermint oil?
Possible side effects of peppermint oil include:
- Allergic reactions such as flushing, headache, and mouth sores.
- Anal burning during bouts of diarrhea.
Is Peppermint a laxative?
Senna tea acts as a stimulant laxative, which works by stimulating the intestines to move stool along. Peppermint tea may help treat and prevent cases of constipation. Peppermint is supposed to be good for digestive health.
Is peppermint oil good for gas and bloating?
Peppermint oil acts as an antispasmodic and relaxes the smooth muscles in the intestine as well as helps to minimize symptoms of indigestion, gas, and bloating, all common with IBS. Purchase the GutBiome Institute recommended peppermint oil supplement.
Is Peppermint anti inflammatory?
Peppermint has antibacterial, antiviral and anti-inflammatory properties. Because of this, peppermint tea may fight clogged sinuses due to infections, the common cold and allergies.
Is Peppermint good for reflux?
Herbal tea
Herbal teas help improve digestion and soothe many stomach problems, such as gas and nausea. Try caffeine-free herbal tea for acid reflux, but avoid spearmint or peppermint teas. Mint triggers acid reflux for many.
Can peppermint raise blood pressure?
The effect of oral peppermint on blood pressure is not consistent, however, our previous animal study has shown that oral administration of menthol, the main component of peppermint, could reduce 24-hour mean arterial systolic and diastolic blood pressure in spontaneous hypertensive rats.
Is Peppermint a blood thinner?
Some herbs and spices that contain salicylates (a natural blood thinner) include cayenne pepper, cinnamon, curry powder, dill, ginger, licorice, oregano, paprika, peppermint, thyme and turmeric. Meanwhile there are fruits that can aid in blood thinning.
Is peppermint oil a probiotic?
Peppermint (Mentha × piperita, Lamiaceae) oil inhibits smooth muscle contraction and has been shown to have a topical effect on the ilea and colon. Probiotics containing species of Bacillus can improve gastrointestinal health and reduce the severity of gastrointestinal symptoms.
Do peppermint capsules work?
Peppermint oil is the most effective treatment for irritable bowel syndrome, according to news reports today. The non-prescription supplement has been shown to be better at easing symptoms than prescribed muscle relaxants or fibre. However, compared to placebo, peppermint oil had the greatest effect.
Is peppermint tea good for skin?
“Peppermint tea is not only a great tea for digestion, but the menthol in it helps to slow down oil production in the skin, which is helpful for anyone with oily, acne prone skin,” Poon says. Bonus: In addition to balancing oil production, peppermint soothes stomachaches.
Does peppermint grow hair?
Peppermint oil can cause a cold, tingling feeling when it increases circulation to the area it's applied to. This can help promote hair growth during the anagen (or growing) phase. One study found that peppermint oil, when used on mice, increased the number of follicles, follicle depth, and overall hair growth.
Can peppermint oil harm you?
Peppermint oil appears to be safe when taken orally (by mouth) in the doses commonly used. Excessive doses of peppermint oil can be toxic. Possible side effects of peppermint oil include allergic reactions and heartburn. Capsules containing peppermint oil are often enteric-coated to reduce the likelihood of heartburn.
What bugs does peppermint oil repel?
Not only does peppermint oil repel ants, it also repels spiders. In fact, peppermint keeps most pests away, including aphids, beetles, caterpillars, fleas, flies, lice, mice and moths.
What happens if you eat too much peppermint candy?
cautions not to eat too much of it. “Peppermint candies are a nutritionally poor food, containing high levels of sugar without any vitamins or minerals. In addition, because peppermint candy contains no fiber, it may encourage overeating by raising your blood sugar and providing little satiation,” it says.
Does peppermint tea make you poop?
Peppermint tea
Peppermint is an herb often used to relieve digestive issues, including IBS. Drinking peppermint tea soothes the intestines, relieves abdominal pain, and reduces bloating. One study found that peppermint also relaxed gastrointestinal tissue in animal models. However, more studies are needed in humans.
Does peppermint get rid of gas?
Peppermint may relieve digestive symptoms, such as gas, bloating and indigestion. Animal studies indicate that peppermint relaxes your digestive system and may ease pain.
Does peppermint oil get rid of gas?
Benefits of Peppermint Oil
Several studies suggest that enteric-coated peppermint oil capsules -- which allow the oil to pass through the stomach so it can dissolve in the intestines -- may help relieve common symptoms of irritable bowel syndrome such as abdominal pain, bloating, and gas.
Is peppermint oil an antifungal?
Types of antifungal essential oils
Citronella, geranium, lemongrass, eucalyptus, and peppermint, among others, have been tested specifically against fungi and found to be effective antimicrobials for that purpose. Tea tree oil is another essential oil that has demonstrated antifungal capabilities.
Is peppermint tea good for kidneys?
In fact, some studies suggest that drinking moderate amounts of tea and coffee can actually decrease the risk of kidney stones. The two to three cups of mint tea you're drinking a day (as well as other herbal teas) should not cause a problem, as long as you're drinking additional amounts of other fluids.
Why is peppermint bad for acid reflux?
Heartburn and Peppermint
Skip the after-dinner mints -- especially after a rich meal. Peppermint may increase your chances of heartburn because it relaxes the sphincter muscle that lay between the stomach and esophagus. This allows stomach acids to flow back into the esophagus.
Clinical Studies
- ^ ab c Leuschner M, et al. Dissolution of gall stones with an ursodeoxycholic acid menthol preparation: a controlled prospective double blind trial. Gut. (1988)
- ^ ab Varney E, Buckle J. Effect of inhaled essential oils on mental exhaustion and moderate burnout: a small pilot study. J Altern Complement Med. (2013)
- ^ ab c d Hiki N, et al. Antiperistaltic effect and safety of L-menthol sprayed on the gastric mucosa for upper GI endoscopy: a phase III, multicenter, randomized, double-blind, placebo-controlled study. Gastrointest Endosc. (2011)
- ^ ab c d Hiki N, et al. An open-label, single-arm study assessing the efficacy and safety of L: -menthol sprayed onto the gastric mucosa during upper gastrointestinal endoscopy. J Gastroenterol. (2011)
- ^ ab c Hiki N, et al. Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy. Dig Endosc. (2012)
- ^ ab c d e f Hiki N, et al. A phase I study evaluating tolerability, pharmacokinetics, and preliminary efficacy of L-menthol in upper gastrointestinal endoscopy. Clin Pharmacol Ther. (2011)
- ^ ab c May B, et al. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung. (1996)
- ^ ab c May B, Köhler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther. (2000)
- ^ ab c Holtmann G, et al. Effects of a fixed combination of peppermint oil and caraway oil on symptoms and quality of life in patients suffering from functional dyspepsia. Phytomedicine. (2003)
- ^ ab Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res. (2000)
- ^ ab Micklefield G, et al. Effects of intraduodenal application of peppermint oil (WS(R) 1340) and caraway oil (WS(R) 1520) on gastroduodenal motility in healthy volunteers. Phytother Res. (2003)
- ^WHO monographs on selected medicinal plants.
- ^ ab c d e f g h i j Grigoleit HG, Grigoleit P. Pharmacology and preclinical pharmacokinetics of peppermint oil. Phytomedicine. (2005)
- ^ ab c Hawthorn M, et al. The actions of peppermint oil and menthol on calcium channel dependent processes in intestinal, neuronal and cardiac preparations. Aliment Pharmacol Ther. (1988)
- ^ ab c d e MECHANISM BY WHICH PEPPERMINT OIL EXERTS ITS RELAXANT EFFECT ON GASTROINTESTINAL SMOOTH MUSCLE.
- ^Gershenzon J, McConkey ME, Croteau RB. Regulation of monoterpene accumulation in leaves of peppermint. Plant Physiol. (2000)
- ^ ab c d e f g h i j k l Regulation of Monoterpene Accumulation in Leaves of Peppermint.
- ^ ab Biosynthesis of (−)-mintlactone and (+)-isomintlactone in Mentha piperita.
- ^Sugiura T, Uchida S, Namiki N. Taste-masking effect of physical and organoleptic methods on peppermint-scented orally disintegrating tablet of famotidine based on suspension spray-coating method. Chem Pharm Bull (Tokyo). (2012)
- ^ ab Kline RM, et al. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. (2001)
- ^Delayed release peppermint oil capsules (Colpermin) for the spastic colon syndrome: a pharmacokinetic study.
- ^ ab c d A pharmacokinetic comparison of two delayed-release peppermint oil preparations, Colpermin and Mintec, for treatment of the irritable bowel syndrome.
- ^Nolen HW 3rd, Friend DR. Menthol-beta-D-glucuronide: a potential prodrug for treatment of the irritable bowel syndrome. Pharm Res. (1994)
- ^Wang LH, Wang CC, Kuo SC. Vehicle and enhancer effects on human skin penetration of aminophylline from cream formulations: evaluation in vivo. J Cosmet Sci. (2007)
- ^ ab c d Kligler B, Chaudhary S. Peppermint oil. Am Fam Physician. (2007)
- ^ ab Göbel H, et al. Effectiveness of Oleum menthae piperitae and paracetamol in therapy of headache of the tension type. Nervenarzt. (1996)
- ^ ab c Göbel H, Schmidt G, Soyka D. Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters. Cephalalgia. (1994)
- ^ ab MacDougall JM, et al. Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues. Chem Res Toxicol. (2003)
- ^ ab Ghazi AM, et al. Effect of mint drink on metabolism of nicotine as measured by nicotine to cotinine ratio in urine of Jordanian smoking volunteers. Nicotine Tob Res. (2011)
- ^ ab Hukkanen J, Jacob P 3rd, Benowitz NL. Metabolism and disposition kinetics of nicotine. Pharmacol Rev. (2005)
- ^ ab Dresser GK, et al. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther. (2002)
- ^Kovar KA, et al. Blood levels of 1,8-cineole and locomotor activity of mice after inhalation and oral administration of rosemary oil. Planta Med. (1987)
- ^Moss M, et al. Modulation of cognitive performance and mood by aromas of peppermint and ylang-ylang. Int J Neurosci. (2008)
- ^Effects of Peppermint Scent Administration on Cognitive Video Game Performance.
- ^Heuberger E, Ilmberger J. The influence of essential oils on human vigilance. Nat Prod Commun. (2010)
- ^ ab c Lane B, et al. Examination of the effectiveness of peppermint aromatherapy on nausea in women post C-section. J Holist Nurs. (2012)
- ^ ab Burns EE, et al. An investigation into the use of aromatherapy in intrapartum midwifery practice. J Altern Complement Med. (2000)
- ^ ab c Tate S. Peppermint oil: a treatment for postoperative nausea. J Adv Nurs. (1997)
- ^ ab Anderson LA, Gross JB. Aromatherapy with peppermint, isopropyl alcohol, or placebo is equally effective in relieving postoperative nausea. J Perianesth Nurs. (2004)
- ^Schoenen J, Timsit-Berthier M. Contingent negative variation: methods and potential interest in headache. Cephalalgia. (1993)
- ^ ab Beesley A, et al. Influence of peppermint oil on absorptive and secretory processes in rat small intestine. Gut. (1996)
- ^Schwartz RK. Olfaction and muscle activity: an EMG pilot study. Am J Occup Ther. (1979)
- ^Tutuian R, Castell DO. Review article: oesophageal spasm - diagnosis and management. Aliment Pharmacol Ther. (2006)
- ^Dalton CB, et al. Diffuse esophageal spasm. A rare motility disorder not characterized by high-amplitude contractions. Dig Dis Sci. (1991)
- ^Allen ML, DiMarino AJ Jr. Manometric diagnosis of diffuse esophageal spasm. Dig Dis Sci. (1996)
- ^ ab Pimentel M, et al. Peppermint oil improves the manometric findings in diffuse esophageal spasm. J Clin Gastroenterol. (2001)
- ^Mizuno S, et al. Oral peppermint oil is a useful antispasmodic for double-contrast barium meal examination. J Gastroenterol Hepatol. (2006)
- ^Imagawa A, et al. Peppermint oil solution is useful as an antispasmodic drug for esophagogastroduodenoscopy, especially for elderly patients. Dig Dis Sci. (2012)
- ^Vakil N, et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. (2006)
- ^Patrick L. Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments. Altern Med Rev. (2011)
- ^ ab c Hills JM, Aaronson PI. The mechanism of action of peppermint oil on gastrointestinal smooth muscle. An analysis using patch clamp electrophysiology and isolated tissue pharmacology in rabbit and guinea pig. Gastroenterology. (1991)
- ^Inamori M, et al. Early effects of peppermint oil on gastric emptying: a crossover study using a continuous real-time 13C breath test (BreathID system). J Gastroenterol. (2007)
- ^Iida H, et al. Early effects of oral administration of lafutidine with peppermint oil, compared with lafutidine alone, on intragastric pH values. Hepatogastroenterology. (2011)
- ^Rees WD, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br Med J. (1979)
- ^Rösch W, et al. Phytotherapy for functional dyspepsia: a review of the clinical evidence for the herbal preparation STW 5. Phytomedicine. (2006)
- ^von Arnim U, et al. STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol. (2007)
- ^Madisch A, et al. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion. (2004)
- ^Fixed peppermint oil/caraway oil combination in functional dyspepsia – efficacy unaffected by H. pylori status.
- ^ ab c Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med. (1980)
- ^Reiter M, Brandt W. Relaxant effects on tracheal and ileal smooth muscles of the guinea pig. Arzneimittelforschung. (1985)
- ^Giachetti D, Taddei E, Taddei I. Pharmacological activity of essential oils on Oddi's sphincter. Planta Med. (1988)
- ^Evans BK, et al. Proceedings: Further studies on the correlation between biological activity and solubility of some carminatives. J Pharm Pharmacol. (1975)
- ^Shavakhi A, et al. Premedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial study. Acta Gastroenterol Belg. (2012)
- ^Suares NC, Ford AC. Diagnosis and treatment of irritable bowel syndrome. Discov Med. (2011)
- ^Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis.
- ^Liu JH, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol. (1997)
- ^Lech Y, et al. Treatment of irritable bowel syndrome with peppermint oil. A double-blind study with a placebo. Ugeskr Laeger. (1988)
- ^Cappello G, et al. Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial. Dig Liver Dis. (2007)
- ^ ab Alam MS, et al. Efficacy of Peppermint oil in diarrhea predominant IBS - a double blind randomized placebo - controlled study. Mymensingh Med J. (2013)
- ^Merat S, et al. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome. Dig Dis Sci. (2010)
- ^Cholertic activity of Thapsia chem I, II, and III in rats: Comparison with terpenoid constituents and peppermint oil.
- ^ ab c d e f Akdoğan M, et al. Effect of spearmint (Mentha spicata Labiatae) teas on androgen levels in women with hirsutism. Phytother Res. (2007)
- ^ ab c Akdogan M, et al. Effects of peppermint teas on plasma testosterone, follicle-stimulating hormone, and luteinizing hormone levels and testicular tissue in rats. Urology. (2004)
- ^Grant P. Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. A randomized controlled trial. Phytother Res. (2010)
- ^ESSENTIAL OILS OF ANATOLIAN LABIATAE: A PROFILE.
- ^Huml S. Sore nipples. A new look at an old problem through the eyes of a dermatologist. Pract Midwife. (1999)
- ^Pugh LC, et al. A comparison of topical agents to relieve nipple pain and enhance breastfeeding. Birth. (1996)
- ^ ab Sayyah Melli M, et al. Effect of peppermint water on prevention of nipple cracks in lactating primiparous women: a randomized controlled trial. Int Breastfeed J. (2007)
- ^Melli MS, et al. A randomized trial of peppermint gel, lanolin ointment, and placebo gel to prevent nipple crack in primiparous breastfeeding women. Med Sci Monit. (2007)
- ^Garten S, Falkner RV. Continual smoking of mentholated cigarettes may mask the early warning symptoms of respiratory disease. Prev Med. (2003)
- ^Giovino GA, et al. Epidemiology of menthol cigarette use. Nicotine Tob Res. (2004)
- ^Benowitz NL, Herrera B, Jacob P 3rd. Mentholated cigarette smoking inhibits nicotine metabolism. J Pharmacol Exp Ther. (2004)
- ^Benowitz NL, et al. Urine menthol as a biomarker of mentholated cigarette smoking. Cancer Epidemiol Biomarkers Prev. (2010)
- ^ ab Hurrell RF, Reddy M, Cook JD. Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages. Br J Nutr. (1999)
- ^Toxicities of peppermint and Pycnanthemum albescens oils.
- ^Thorup I, et al. Short term toxicity study in rats dosed with pulegone and menthol. Toxicol Lett. (1983)
- ^Herro E, Jacob SE. Mentha piperita (peppermint). Dermatitis. (2010)
- ^Anal burning and peppermint oil.