Olive
Overview
Olive is a tree. People use the oil from the fruit and seeds, water extracts of the fruit, and the leaves to make medicine.
Olive oil is most commonly used for heart disease, high cholesterol, and high blood pressure.
In foods, olive oil is used as a cooking and salad oil. Olive oil is classified, in part, according to acid content, measured as free oleic acid. Extra virgin olive oil contains a maximum of 1% free oleic acid, virgin olive oil contains 2%, and ordinary olive oil contains 3.3%. Unrefined olive oils with more than 3.3% free oleic acid are considered "unfit for human consumption."
In manufacturing, olive oil is used to make soaps, commercial plasters and liniments; and to delay setting in dental cements.
Classification
Is a Form of:
Tree
Primary Functions:
Heart disease, high cholesterol, and high blood pressure
Also Known As:
Acide Gras Insaturé, Acide Gras Mono-Insaturé, Acide Gras n-9, Acide Gras Oméga 9, Common Olive, Extra Virgin Olive Oil
How Does It Work?
Fatty acids in olive oil seem to decrease cholesterol levels and have anti-inflammatory effects. Olive leaf and olive oil might lower blood pressure. Olive might also be able to kill microbes, such as bacteria and fungus.
Uses
- Breast cancer. Women who consume more olive oil in their diet seem to have a lower risk of developing breast cancer.
- Heart disease. People who cook using olive oil seem to have a lower risk of heart disease and lower risk of first heart attack compared to those who cook with other oils. People who replace saturated fats in their diet with olive oil also seem to have a lower blood pressure and lower cholesterol compared to those who consume more saturated fat in their diet. High cholesterol and high blood pressure are risk factors for heart disease. Research also shows that following a diet that includes olive oil also reduce the risk of heart attack, stroke, and heart disease-related death compared to following the same diet that includes less olive oil. The FDA allows labels on olive oil and on food that contains olive oil to state that limited, but not conclusive evidence, suggests that consuming 23 grams/day (about 2 tablespoons) of olive oil instead of saturated fats may reduce the risk of heart disease. The FDA also allows products containing certain forms of olive oil to claim that consuming these products can reduce the risk of heart disease. It's unclear if higher dietary intake of olive oil is beneficial in people who already have heart disease. Results from research are conflicting.
- Constipation. Taking olive oil by mouth can help to soften stools in people with constipation.
- Diabetes. People who eat higher amounts of olive oil (about 15-20 grams per day) seem to have a lower risk of developing diabetes. Eating more than 20 grams per day is not linked with additional benefit. Research also shows that olive oil can improve blood sugar control in people with diabetes. Olive oil in a Mediterranean-type diet might also reduce the risk of "hardening of the arteries" (atherosclerosis) compared to polyunsaturated oils such as sunflower oil in people with diabetes.
- High cholesterol. Using olive oil in the diet instead of saturated fat may reduce total cholesterol levels in people with high cholesterol. But other dietary oils might reduce total cholesterol better than olive oil.
- High blood pressure. Adding generous amounts of extra virgin olive oil to the diet and continuing with the usual treatments for high blood pressure can improve blood pressure over 6 months in people with high blood pressure. In some cases, people with mild to moderate high blood pressure can actually lower their dose of blood pressure medication or even stop taking medication altogether. However, do not adjust your medications without your healthcare provider's supervision. Taking olive leaf extract also seems to lower blood pressure in patients with high blood pressure.
Recommended Dosing
The following doses have been studied in scientific research:
BY MOUTH:
- For constipation: 30 mL of olive oil.
- For preventing heart disease: 54 grams of olive oil per day (about 4 tablespoons) has been used. As a part of a Mediterranean diet, consuming up to 1 liter of extra-virgin olive oil per week has also been used.
- For preventing diabetes. A diet rich in olive oil has been used. Doses of 15-20 grams per day seem to work best.
- For high cholesterol: 23 grams of olive oil per day (about 2 tablespoons) providing 17.5 grams of monounsaturated fatty acids in place of saturated fats in the diet.
- For high blood pressure: 30-40 grams per day of extra-virgin olive oil as part of the diet. 400 mg of olive leaf extract four times daily has also been used for high blood pressure.
Olive Supplements Asked Questions
What does olives do in a woman's body?
Skin and hair health
Black olives are rich in fatty acids and antioxidants that nourish, hydrate and protect. Chief among those is vitamin E. Whether applied topically or ingested, vitamin E has been shown to protect skin from ultraviolet radiation, thus guarding against skin cancer and premature aging.
How many olives should you eat a day?
Olives provide some fibre, vitamin E and healthy monounsaturated oils. And yes, they do count towards your 5-a-day portions. However, a portion of olives is about 80 grams weighed without the stones, which means you need to eat around 30 olives to make up one portion.
What is the healthiest olive?
While Kalamata olives are high in fat considering their serving size, the majority of their fat is monounsaturated, also known as a “healthy” fat. It is said a 4-tablespoon serving of Kalamata olives has 2.7 grams of monounsaturated fats, and 0.3 grams of polyunsaturated fats.
What vitamins are in olives?
Nutritionally, olives are a good source of a few micronutrients including vitamin E, iron, copper and calcium. Vitamin E is a powerful antioxidant that helps protect our cells from oxidative damage, and there is evidence that this vitamin may play a role in obesity.
Can I eat olives everyday?
By eating a daily serving of healthy olives you can help improve your memory. Remember that! Beauty – Eating healthy olives helps skin stay soft and healthy since they contain oleic acid. Appetite control – By eating a few olives before a meal, you can take the edge off your appetite.
What happens if you eat too many olives?
Olives are a good source of oleate, which is a monounsaturated fatty acid. Over time, excess levels of salt in the body can lead to high blood pressure, heart attacks, and stroke, so people should eat olives in moderation.
Can olives make you fat?
Though olives may aid weight loss, they're high in salt and fat — and eating too many of them may offset your weight loss success. As such, you should moderate your intake, limiting yourself to a few ounces at most per day.
Are olives in a jar good for you?
Olives are typically high in salt due the fact that they are cured or packaged in brine or salt water, containing about 0.5g salt per five olives. Nutritionally, olives are a good source of a few micronutrients including vitamin E, iron, copper and calcium.
What is olive leaf capsules good for?
Summary. Preliminary studies suggest that olive leaf extract may have several health benefits. These include lowering blood pressure, improving cholesterol levels, and reducing the risk of weight gain and type 2 diabetes.
Can you take olive leaf extract every day?
Dosage and Preparation
There is no recommended daily allowance for olive leaf extract. The standard dose ranges from 500 mg to 1,000 mg daily. Most supplement labels recommend splitting the dose, taking 250 mg to 500 mg two to four times a day with food.
How fast does olive leaf extract work?
After eight weeks, the olive leaf extract led to significantly lower blood pressure, with the higher dose having a greater effect. The most recent study, published earlier this year, was a randomised controlled study.
Can olive leaf extract make you sick?
If you feel under the weather after taking olive leaf extract — headaches, joint pains, flu-like symptoms — you're likely experiencing the die-off effect. Try increasing your fluid intake, and if the symptoms are too much to handle, decrease your olive leaf dosage to a manageable level.
What happens if you drink olive oil everyday?
Summary Olive oil is a healthy fat that contains anti-inflammatory compounds. Drinking it regularly may benefit your heart, bone, and digestive health and help stabilize your blood sugar levels.
Why olive oil is bad for you?
Bottom Line: Research has shown in both humans and other primates that diets high in fat and cholesterol promote atherosclerosis. ... “So while olive oil may be less bad than saturated fats and trans fats at least in terms of its impact on blood lipids, that hardly makes it a 'good' or 'healthy' addition to your diet.”
Does olive oil clog arteries?
Caldwell Esselstyn points out, “Between 14 and 17 percent of olive oil is saturated, artery-clogging fat—every bit as aggressive in promoting heart disease as the saturated fat in roast beef.”
Is olive leaf good for kidneys?
Olive leaf extract (OLE) has been demonstrated to have antioxidant and anti-inflammatory effects. Conclusions: Olive leaf extract ameliorates gentamicin nephrotoxicity via antioxidant activity, increase of renal glutathione content, and increase of renal antioxidant enzymes activity, except for glutathione peroxidase.
Does olive leaf extract kill good gut bacteria?
Olive leaf contains a substance called oleuropein, which breaks down in the body to another substance called enolinate. On websites that promote olive leaf extracts, it is stated that enolinate kills harmful bacteria, viruses, and fungi in the body, but at the same time nurtures microbes that are good for health.
Is olive leaf extract bad for your liver?
The olive leaves extract should be handled with care in arts and other animals and special attention should be paid when using OLE for longer periods of time and at higher doses as it may result in an undesirable effect on liver and kidneys as it has been shown in the present study.
Does olive leaf extract boost immune system?
Olive Leaf Extract helps to strengthen the immune system, remove toxins from the body and promote overall good health. Olive leaves have traditionally been used to enhance the functioning of the immune system and aid the management of viral infections, especially when fever is present.
Can I take olive oil before bed?
Pre-sleep quality olive oil treatment is being suggested to those with insomnia who would like to be able to fall asleep as well as improve the quality of the given rest throughout the night. This anti-inflammatory health benefit is possible once a good olive oil is taken consistently before retiring at night.
Can you take olive oil orally?
Due to the numerous health benefits of olive oil, it is typically used in cooking, but eating it raw is even healthier. A lot of health experts recommend eating olive oil in the morning, with just a dash of lemon juice. The lemon is added to make the oil more palatable and also give a boost to the digestive system.
Is coconut oil better than olive oil?
In terms of health impacts, it is better to cook with olive oil. Compared to a tablespoon of olive oil, a tablespoon of coconut oil contains about six times the amount of saturated fat, nearly meeting the daily limit of about 13 grams that the American Heart Association recommends.
Clinical Studies
- ^ a b c d e f Identification of Anti-α-Amylase Components from Olive Leaf Extracts.
- ^ a b c d e f Susalit E, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine. (2011)
- ^ a b c d e f g h i Somova LI, et al. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J Ethnopharmacol. (2003)
- ^ Imithi yamasiko - culturally useful plants in the Peddie district of the Eastern Cape with specific reference to Olea europaea subsp. africana.
- ^ a b c d e f Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. (2010)
- ^ 1 H and 13C NMR characterization of new oleuropein aglycones.
- ^ a b Isolation of cornoside from Olea europaea and its transformation into halleridone.
- ^ Accumulation of oleuropein derivatives during olive maturation.
- ^ a b c d e f g h i j k l m n o p de Bock M, et al. Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial. PLoS One. (2013)
- ^ a b c d e f g h i Hansen K, et al. Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea. Phytomedicine. (1996)
- ^ a b Perrinjaquet-Moccetti T, et al. Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytother Res. (2008)
- ^ a b c d e f Phytochemical analysis and gastroprotective activity of an olive leaf extract.
- ^ Phenolic Compounds and Antioxidant Activity of Olea europaea L. Fruits and Leaves.
- ^ a b c d e f Poudyal H, Campbell F, Brown L. Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. J Nutr. (2010)
- ^ Sánchez-González M, et al. Assessment of the safety of maslinic acid, a bioactive compound from Olea europaea L. Mol Nutr Food Res. (2013)
- ^ Alqahtani A, et al. The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications. Curr Med Chem. (2013)
- ^ Quirantes-Piné R, et al. HPLC-ESI-QTOF-MS as a Powerful Analytical Tool for Characterising Phenolic Compounds in Olive-leaf Extracts. Phytochem Anal. (2012)
- ^ a b c Biophenolic components of olives.
- ^ Venditti A, et al. Aromadendrine, a new component of the flavonoid pattern of Olea europaea L. and its anti-inflammatory activity. Nat Prod Res. (2013)
- ^ El SN, Karakaya S. Olive tree (Olea europaea) leaves: potential beneficial effects on human health. Nutr Rev. (2009)
- ^ Gandul-Rojas B, Cepero MR, Mínguez-Mosquera MI. Chlorophyll and carotenoid patterns in olive fruits, Olea europaea Cv. arbequina. J Agric Food Chem. (1999)
- ^ Ryan D, et al. Liquid chromatography with electrospray ionisation mass spectrometric detection of phenolic compounds from Olea europaea. J Chromatogr A. (1999)
- ^ Brenes M, et al. Rapid and complete extraction of phenols from olive oil and determination by means of a coulometric electrode array system. J Agric Food Chem. (2000)
- ^ Franconi F, et al. Antioxidant effect of two virgin olive oils depends on the concentration and composition of minor polar compounds. J Agric Food Chem. (2006)
- ^ Brenes M, et al. Acid hydrolysis of secoiridoid aglycons during storage of virgin olive oil. J Agric Food Chem. (2001)
- ^ Pinoresinol and 1-acetoxypinoresinol, two new phenolic compounds identified in olive oil.
- ^ a b HPLC/DAD/ESI/MS detection of lignans from Spanish and Italian Olea europaea L. fruits.
- ^ a b Owen RW, et al. Identification of lignans as major components in the phenolic fraction of olive oil. Clin Chem. (2000)
- ^ Japón-Luján R, Luque-Rodríguez JM, Luque de Castro MD. Dynamic ultrasound-assisted extraction of oleuropein and related biophenols from olive leaves. J Chromatogr A. (2006)
- ^ Importance and evolution of phenolic compounds in olive during growth and maturation.
- ^ a b Tuck KL, Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem. (2002)
- ^ Agati G, et al. Nondestructive evaluation of anthocyanins in olive (Olea europaea) fruits by in situ chlorophyll fluorescence spectroscopy. J Agric Food Chem. (2005)
- ^ Panzanaro S, et al. Biochemical characterization of a lipase from olive fruit (Olea europaea L.). Plant Physiol Biochem. (2010)
- ^ Yanik H, et al. Genome-wide identification of alternate bearing-associated microRNAs (miRNAs) in olive (Olea europaea L.). BMC Plant Biol. (2013)
- ^ a b Svobodova M1, et al. Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma. Genes Nutr. (2014)
- ^ Manna C, et al. Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells. FEBS Lett. (2000)
- ^ a b Visioli F, et al. Olive oil phenolics are dose-dependently absorbed in humans. FEBS Lett. (2000)
- ^ a b Vissers MN, et al. Olive oil phenols are absorbed in humans. J Nutr. (2002)
- ^ a b Corona G, et al. The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation. Free Radic Res. (2006)
- ^ Oleuropein, an Antioxidant Polyphenol from Olive Oil, Is Poorly Absorbed from Isolated Perfused Rat Intestine.
- ^ Ciafardini G, et al. Hydrolysis of Oleuropein by Lactobacillus plantarum Strains Associated with Olive Fermentation. Appl Environ Microbiol. (1994)
- ^ Pinto J, et al. Absorption and metabolism of olive oil secoiridoids in the small intestine. Br J Nutr. (2011)
- ^ Tan HW, et al. Simultaneous determination of oleuropein and hydroxytyrosol in rat plasma using liquid chromatography with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. (2003)
- ^ Del Boccio P, et al. Liquid chromatography-tandem mass spectrometry analysis of oleuropein and its metabolite hydroxytyrosol in rat plasma and urine after oral administration. J Chromatogr B Analyt Technol Biomed Life Sci. (2003)
- ^ a b De Nicoló S, et al. Effects of olive polyphenols administration on nerve growth factor and brain-derived neurotrophic factor in the mouse brain. Nutrition. (2013)
- ^ Ibi M, et al. NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth. Free Radic Biol Med. (2006)
- ^ Gundimeda U, et al. Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species. J Neurosci Res. (2010)
- ^ Pasban-Aliabadi H, et al. Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein. Rejuvenation Res. (2013)
- ^ a b c Kaeidi A, et al. Olive (Olea europaea L.) leaf extract attenuates early diabetic neuropathic pain through prevention of high glucose-induced apoptosis: in vitro and in vivo studies. J Ethnopharmacol. (2011)
- ^ Khayyal MT, et al. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittelforschung. (2002)
- ^ Lasserre B, et al. Effects on rats of aqueous extracts of plants used in folk medicine as antihypertensive agents. Naturwissenschaften. (1983)
- ^ a b c d Gimeno E, et al. Changes in the phenolic content of low density lipoprotein after olive oil consumption in men. A randomized crossover controlled trial. Br J Nutr. (2007)
- ^ a b c Covas MI, et al. The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial. Ann Intern Med. (2006)
- ^ a b c d Marrugat J, et al. Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation--a randomized controlled trial. Eur J Nutr. (2004)
- ^ a b Rietjens SJ, Bast A, Haenen GR. New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. J Agric Food Chem. (2007)
- ^ Lapointe A, Couillard C, Lemieux S. Effects of dietary factors on oxidation of low-density lipoprotein particles. J Nutr Biochem. (2006)
- ^ Raederstorff D. Antioxidant activity of olive polyphenols in humans: a review. Int J Vitam Nutr Res. (2009)
- ^ Covas MI, et al. Postprandial LDL phenolic content and LDL oxidation are modulated by olive oil phenolic compounds in humans. Free Radic Biol Med. (2006)
- ^ a b Fitó M, et al. Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: a randomized, crossover, controlled, clinical trial. Atherosclerosis. (2005)
- ^ a b Weinbrenner T, et al. Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men. J Nutr. (2004)
- ^ Visioli F, Galli C. Antiatherogenic components of olive oil. Curr Atheroscler Rep. (2001)
- ^ Carluccio MA, et al. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. (2003)
- ^ a b Castañer O, et al. Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans. Am J Clin Nutr. (2012)
- ^ a b c Sato H, et al. Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochem Biophys Res Commun. (2007)
- ^ a b A G Protein-coupled Receptor Responsive to Bile Acids.
- ^ a b Watanabe M, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. (2006)
- ^ a b Baxter JD, Webb P. Metabolism: bile acids heat things up. Nature. (2006)
- ^ Al-Qarawi AA, Al-Damegh MA, ElMougy SA. Effect of freeze dried extract of Olea europaea on the pituitary-thyroid axis in rats. Phytother Res. (2002)
- ^ a b Oi-Kano Y, et al. Extra virgin olive oil increases uncoupling protein 1 content in brown adipose tissue and enhances noradrenaline and adrenaline secretions in rats. J Nutr Biochem. (2007)
- ^ a b c Oi-Kano Y, et al. Oleuropein supplementation increases urinary noradrenaline and testicular testosterone levels and decreases plasma corticosterone level in rats fed high-protein diet. J Nutr Biochem. (2012)
- ^ a b Heinze JE, Hale AH, Carl PL. Specificity of the antiviral agent calcium elenolate. Antimicrob Agents Chemother. (1975)
- ^ a b Renis HE. In vitro antiviral activity of calcium elenolate. Antimicrob Agents Chemother (Bethesda). (1969)
- ^ Ali NH1, Faizi S, Kazmi SU. Antibacterial activity in spices and local medicinal plants against clinical isolates of Karachi, Pakistan. Pharm Biol. (2011)
- ^ Sudjana AN1, et al. Antimicrobial activity of commercial Olea europaea (olive) leaf extract. Int J Antimicrob Agents. (2009)
- ^ Markin D1, Duek L, Berdicevsky I. In vitro antimicrobial activity of olive leaves. Mycoses. (2003)
- ^ Lee OH1, Lee BY. Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresour Technol. (2010)
- ^ Soret MG. Antiviral activity of calcium elenolate on parainfluenza infection of hamsters. Antimicrob Agents Chemother (Bethesda). (1969)
- ^ Knipping K1, Garssen J, van't Land B. An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts. Virol J. (2012)
- ^ Micol V1, et al. The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res. (2005)
- ^ Lee-Huang S1, et al. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem Biophys Res Commun. (2003)
- ^ Manna C, et al. Biological effects of hydroxytyrosol, a polyphenol from olive oil endowed with antioxidant activity. Adv Exp Med Biol. (1999)
- ^ Visioli F, Poli A, Gall C. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev. (2002)
- ^ Blekas G, et al. Biophenols in table olives. J Agric Food Chem. (2002)
- ^ Kim JS, Kwon CS, Son KH. Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid. Biosci Biotechnol Biochem. (2000)
- ^ a b Wainstein J, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food. (2012)
- ^ a b Cvjetićanin T, et al. Dried leaf extract of Olea europaea ameliorates islet-directed autoimmunity in mice. Br J Nutr. (2010)
- ^ El-Amin M, et al. Anti-diabetic effect of Murraya koenigii (L) and Olea europaea (L) leaf extracts on streptozotocin induced diabetic rats. Pak J Pharm Sci. (2013)
- ^ a b c Eidi A, Eidi M, Darzi R. Antidiabetic effect of Olea europaea L. in normal and diabetic rats. Phytother Res. (2009)
- ^ Neves JM, et al. Ethnopharmacological notes about ancient uses of medicinal plants in Trás-os-Montes (northern of Portugal). J Ethnopharmacol. (2009)
- ^ Leporatti ML, Ivancheva S. Preliminary comparative analysis of medicinal plants used in the traditional medicine of Bulgaria and Italy. J Ethnopharmacol. (2003)
- ^ Koca U, et al. Wound repair potential of Olea europaea L. leaf extracts revealed by in vivo experimental models and comparative evaluation of the extracts' antioxidant activity. J Med Food. (2011)
- ^ Perugini P, et al. Efficacy of oleuropein against UVB irradiation: preliminary evaluation. Int J Cosmet Sci. (2008)
- ^ a b Sumiyoshi M, Kimura Y. Effects of olive leaf extract and its main component oleuroepin on acute ultraviolet B irradiation-induced skin changes in C57BL/6J mice. Phytother Res. (2010)
- ^ Kimura Y, Sumiyoshi M. Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. J Nutr. (2009)
- ^ Türkez H, Toğar B. Olive (Olea europaea L.) leaf extract counteracts genotoxicity and oxidative stress of permethrin in human lymphocytes. J Toxicol Sci. (2011)
- ^ a b c Tunca B, et al. Olea europaea leaf extract alters microRNA expression in human glioblastoma cells. J Cancer Res Clin Oncol. (2012)
- ^ Abaza L, et al. Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract. Biosci Biotechnol Biochem. (2007)
- ^ Fares R, et al. The antioxidant and anti-proliferative activity of the Lebanese Olea europaea extract. Plant Foods Hum Nutr. (2011)
- ^ a b Reyes FJ, et al. (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells. FEBS Lett. (2006)
- ^ Mijatovic SA, et al. Multiple antimelanoma potential of dry olive leaf extract. Int J Cancer. (2011)
- ^ The Spectrum of Olive Pollen Allergens.
- ^ a b Florido Lopez JF, et al. An allergen from Olea europaea pollen (Ole e 7) is associated with plant-derived food anaphylaxis. Allergy. (2002)
- ^ Pastorello EA, et al. Clinical role of a lipid transfer protein that acts as a new apple-specific allergen. J Allergy Clin Immunol. (1999)
- ^ Marazuela EG, et al. A non-allergenic Ole e 1-like protein from birch pollen as a tool to design hypoallergenic vaccine candidates. Mol Immunol. (2012)
- ^ Fritsch R, et al. Bet v 1, the major birch pollen allergen, and Mal d 1, the major apple allergen, cross-react at the level of allergen-specific T helper cells. J Allergy Clin Immunol. (1998)
- ^ Asero R. Effects of birch pollen-specific immunotherapy on apple allergy in birch pollen-hypersensitive patients. Clin Exp Allergy. (1998)
- ^ Mauro M, et al. Birch-apple syndrome treated with birch pollen immunotherapy. Int Arch Allergy Immunol. (2011)