Glucosamine sulphate is a chemical that naturally occurs in the fluid around the joints of the human body, which uses it to produce other chemicals that help build cartilage, tendons, ligaments and the fluid surrounding joints. The fluid and the cartilage cushion the joints. As people age, their glucosamine levels decline which can cause the joint to deteriorate. In addition, osteoarthritis can cause the cartilage to break down which causes joint pain and stiffness.

Glucosamine sulphate is most often used (sometimes in conjunction with chondroitin and/or MSM)  to treat the joint pain caused by osteoarthritis. Researchers believe that the supplement may either increase the amount of cartilage and fluid surrounding the joints, prevent them from breaking down, or both. Glucosamine has also been used to treat allergies, asthma, chronic low back pain, inflammatory bowel disease, rheumatoid arthritis, sports injuries, and TMJ problems.

Glucosamine sulphate supplements are made from the outer shells of shellfish. It is not found in any foods.

A doctor will typically prescribe a dosage of 500 milligrams of glucosamine sulfate taken up to three times a day.